Polystyrene microplastics induce anxiety via HRAS derived PERK-NF-κB pathway
Abstract
PS-MPs induced anxiety-like behavior and accumulated in the brain of mice. PS-MPs-induced toxicity was related to inflammation pathways. HRAS was identified as a key factor in PS-MPs induced pro-inflammatory response. HRAS induced PERK-NF-κB pathway played a significant role in PS-MPs induced toxicity.
- Publication:
-
Environment International
- Pub Date:
- March 2024
- DOI:
- 10.1016/j.envint.2024.108543
- Bibcode:
- 2024EnInt.18508543L
- Keywords:
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- Polystyrene microplastics;
- Environmental toxicology;
- Analytical chemistry