DNA methylation clocks for dogs and humans
Abstract
Epigenetic estimators of age (known as clocks) allow one to identify interventions that slow or reverse aging. Previous epigenetic clocks only applied to one species at a time. Here, we describe epigenetic clocks that apply to both dogs and humans. These clocks, which measure methylation levels in highly conserved stretches of the DNA, promise to increase the likelihood that interventions that reverse epigenetic age in one species will have the same effect in the other.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- May 2022
- DOI:
- 10.1073/pnas.2120887119
- Bibcode:
- 2022PNAS..11920887H