Flavonoid Derivatives from The Leaves of Muntingiacalabura L.
Abstract
The Isolation and Purification of ethyl acetate fraction from Muntingiacalabura leaves have resulted three flavonoid derivatives. UV-Vis, 1H-NMR dan13C-NMR data showed that isolate compounds are 2’,4’-dihydroxychalcone (1), 3,7-dimetoxy-5-hydroxyflavone (2), and 3,5,7-trihydroxy-8-methoxyflavone (3). The antioxidant evaluation against 2,2-diphenyl-1-picrylhydrazyl (DPPH), compound (3), showedto be a very high activity (IC503,7 × 109 ppm). The isolated compounds were also evaluated for their cytotoxic activities against murine leukemia P-388 cells resulted that all isolated compounds were inactive.
- Publication:
-
Journal of Physics Conference Series
- Pub Date:
- March 2020
- DOI:
- 10.1088/1742-6596/1485/1/012030
- Bibcode:
- 2020JPhCS1485a2030K