Replacing P-values with frequentist posterior probabilities of replication—When possible parameter values must have uniform marginal prior probabilities
Abstract
Possible parameter values in a random sampling model are shown by definition to have uniform base-rate prior probabilities. This allows a frequentist posterior probability distribution to be calculated for such possible parameter values conditional solely on actual study observations. If the likelihood probability distribution of a random selection is modelled with a symmetrical continuous function then the frequentist posterior probability of something equal to or more extreme than the null hypothesis will be equal to the P-value; otherwise the P value would be an approximation. An idealistic probability of replication based on an assumption of perfect study methodological reproducibility can be used as the upper bound of a realistic probability of replication that may be affected by various confounding factors. Bayesian distributions can be combined with these frequentist distributions. The idealistic frequentist posterior probability of replication may be easier than the P-value for non-statisticians to understand and to interpret.
- Publication:
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PLoS ONE
- Pub Date:
- February 2019
- DOI:
- 10.1371/journal.pone.0212302
- arXiv:
- arXiv:1710.07284
- Bibcode:
- 2019PLoSO..1412302L
- Keywords:
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- Statistics - Other Statistics
- E-Print:
- 14 pages, 4 figures