Peptide regulation of plant and animal morphogenesis: general mechanisms and specificity of action
Abstract
Regulatory peptides are one of the main signaling molecules that provide intercellular interactions in biological systems. Thus, regulatory peptides are known as morphogens - biologically active substances involved in the regulation of the morphogenesis of animals and plants. Until now, the interaction of plant and animal peptides and, in particular, the ‘cross’ effect of plant peptides on the morphogenesis of animals and vice versa has not been sufficiently investigated.
The present work is devoted to the study of the effect of growth regulator peptide (CLV 3) of Arabidopsis on the morphogenesis of animals - freshwater flatworms - planaria. This peptide is an effective regulator of growth and differentiation of plant roots in low and ultra-low concentrations. Various biophysical methods have shown that this plant peptide at a concentration of 10-9M is also an effective morphogen of animals. At the same time, the specificity of the action of peptides on ‘unrelated’ biological targets has been found. The peptide CLV 3 stimulates on the morphogenesis of plant roots in concentrations up to 10-12M, while for planarian regeneration it acts only at concentrations up to 10-9M, at which it does not show a noticeable effect on root plant growth. When this peptide was applied to the of stem human stem cells Th culture, there was no effect observed. The results of the study confirm the thesis that there is a general biological level and peptide regulation mechanisms that are similar for animals and plants, and also reveal the nature of the specifics of the ‘direct’ and ‘cross’ action of this mechanism.- Publication:
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Materials Science and Engineering Conference Series
- Pub Date:
- February 2019
- DOI:
- 10.1088/1757-899X/487/1/012020
- Bibcode:
- 2019MS&E..487a2020T