a Picture of the Gly-Pro Sequence of Collagen is Caught in Gas Phase
Abstract
The structure of the Gly-Pro and Pro-Gly dipeptides have been studied by laser ablation chirped pulse and molecular beam Fourier transform microwave (LA-CP-FTMW and LA-MB-FTMW) spectroscopy. While three conformers of Gly-Pro have been characterized only one conformer has been found in Pro-Gly. Interestingly, the resemblance of the structure determined in Gly-Pro and that observed in the crystal of a collagen-like peptide is striking.
Bermúdez, C.; Mata, S.; Cabezas, C.; Alonso, J. L., Tautomerism in Neutral Histidine. Angew. Chem. Int. Ed. 53, 11015-11018 (2014). J. L. Alonso and J. C. López, in Gas-Phase IR Spectroscopy and Structure of Biological Molecules, eds. A. M. Rijs and J. Oomens, Topics in., 2015, vol. 364, pp. 335-402.- Publication:
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73rd International Symposium on Molecular Spectroscopy
- Pub Date:
- June 2018
- DOI:
- 10.15278/isms.2018.ML02
- Bibcode:
- 2018isms.confEML02L
- Keywords:
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- Structure determination