A Novel Radiation Particle Trajectory Assessment: Imaging of Heavy Ion Tracks at Cell Level
Abstract
Recently, we developed a radiation detector system to characterize heavy ion particle trajectory at micron resolution (utilizing a 1.67 microns per pixel sensor). The CMOS (Complementary Metal Oxide Semiconductor) sensor used to develop the detector system has an active array of 3664 x 2748 pixels in about 6.1 mm x 4.6 mm dimensions. We also incorporated a holder for chamber slides to be positioned and placed on top of the CMOS sensor. The chamber slide with appropriate biological cell structure, once positioned precisely on the pixel array sensor and exposed to the radiation, the particle trajectory from the sensor data at 1.67 micron resolution can be correlated for the observed particle induced damage at the cell level. Our preliminary studies with heavy ions as part of the NASA Space Radiation Laboratory (NSRL) experiments at Brookhaven National Laboratory (BNL) are very promising with H, He, C, O, Si, and Fe ions. Our preliminary assessment of radiation particle trajectory from the sensor data has been correlated with several biological samples including mCherry 53BP1 mouse hippocampal neuronal cells. We present our preliminary approach in the development of our pixel array radiation detector system and correlate radiation particle induced damage at the cell level. Also, we present our observed radiation track image data of heavy ions at cell dimensions.
- Publication:
-
42nd COSPAR Scientific Assembly
- Pub Date:
- July 2018
- Bibcode:
- 2018cosp...42E2938S