Electrochemical and theoretical characterization of the electro-oxidation of dimethoxycurcumin
Abstract
Dimethoxycurcumin (DMC) ((1E,6E)-1-(3,4-dimethoxycyclohexyl)-7-(3,4-dimethoxyphenyl) hepta-1,6- diene-3,5-dione) is a natural polyphenolic compound that appears together with curcumin in turmeric. Both molecules have wide range biological activities as antioxidant, anti-inflammatory and anti-carcinogenic agent. To evaluate the oxidation process and kinetics for DMC, the rate constant, electron transfer and diffusion coefficients for the electrochemical oxidation were determined. Therefore, its electrochemical behavior over a platinum electrode in anhydrous media was investigated. Furthermore, DFT calculations were performed to give a rational explanation to the obtained results. All the results support the fact that the central sbnd CH2sbnd group is the most reactive against an oxidation process.
- Publication:
-
Chemical Physics Letters
- Pub Date:
- June 2017
- DOI:
- 10.1016/j.cplett.2017.03.067
- Bibcode:
- 2017CPL...677...35A
- Keywords:
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- Electrochemical oxidation;
- Dimethoxycurcumin;
- DFT;
- Voltammetry