Phylogenomic analysis reveals ancient segmental duplications in the human genome
Abstract
Evolutionary history of human FGFR-bearing paralogon was investigated. Phylogenies of 80 gene-families by employing sequences from diverse animal species. Results corroborate that small-scale duplications structured human FGFR-bearing paralogon. These regional duplications occurred at different time points in animal history. These data contradict the assumption of WGDs at the root of vertebrate lineage.
- Publication:
-
Molecular Phylogenetics and Evolution
- Pub Date:
- January 2016
- DOI:
- 10.1016/j.ympev.2015.08.019
- Bibcode:
- 2016MolPE..94...95H
- Keywords:
-
- FGFR;
- Phylogeny;
- Gene duplications;
- Whole genome duplications;
- Vertebrates;
- Human chromosomes;
- Paralogon