Formation of periodic nanostructures using a femtosecond laser to control cell spreading on titanium
Abstract
Although titanium (Ti) is a common biomaterial, controlling cell spreading by forming periodic structures using a femtosecond laser should improve its biocompatibility. Herein we investigate the influence of periodic nanostructures formed on the surface of a Ti plate on cell spreading. Nanostructures with a periodicity of 590 nm are formed using a femtosecond laser with a wavelength of 775 nm. Cell spreading on the plate without period structures lacks a definite direction, whereas cell spreading on the Ti plate with periodic structures occurs along the grooves, suggesting that forming periodic structures via a femtosecond laser can control cell spreading.
- Publication:
-
Applied Physics B: Lasers and Optics
- Pub Date:
- June 2015
- DOI:
- 10.1007/s00340-015-6082-4
- Bibcode:
- 2015ApPhB.119..493S