New self-dualities involving two index tensors are derived. These new self-dualities are used to build various duality cascades. Both vectorlike and chiral cascades are presented. Aside from ending in confinement, these duality cascades can also end in interacting conformal field theories, free field theories, and metastable supersymmetry breaking. Higgsing effects are built into the self-duality so that when the gauge groups are small enough, supersymmetry is broken through the rank condition. Dynamical supersymmetry restoration occurs far from the SUSY breaking vacuum resulting in a long-lived metastable vacuum. It is found that Coulomb branches are critical in the stabilization of runaways and dynamical supersymmetry restoration.