PRP8 intein in cryptic species of Histoplasma capsulatum: Evolution and phylogeny
Abstract
The PRP8 intein was identified in a total of 99 Histoplasma capsulatum isolates. All HcaPRP8 inteins present both Splicing and Homing Endonuclease domains. The phylogeny of the PRP8 intein places the LAmB and H81 lineage isolates inside the LAmA clade, probable due to eventual population admixture or shared ancestral polymorphism. The PRP8 intein phylogeny can distinguish the cryptic species of the genus Histoplasma.
- Publication:
-
Infection, Genetics and Evolution
- Pub Date:
- August 2013
- DOI:
- 10.1016/j.meegid.2013.05.001
- Bibcode:
- 2013InfGE..18..174T
- Keywords:
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- Histoplasma capsulatum;
- Latin America;
- PRP8 intein;
- Phylogeny