New optical reference standard in the field of biology: interrogation of micro-resonator based biosensor with a phase sensitive-optical low coherence interferometer
Abstract
A phase-sensitive optical low coherence interferometer is investigated experimentally to implement a new optical reference standard in the field of biology. This interrogation technique is associated to a planar cyclic resonant sensor such as an optical waveguide-based micro-cavity. The biological solution to be analyzed will be brought onto the surface of the sensor through a micro-fluidic cell. The aim of this association is to quantify low concentrations of analytes and to realize a real-time investigation of the kinetics of specific molecules with time and temperature for metrological applications, with better sensitivity and accuracy than existing techniques. This paper deals with the results of a feasibility study on the PS-OLCI technique as a new reference in the field of biology.
- Publication:
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Optical Sensors 2011; and Photonic Crystal Fibers V
- Pub Date:
- May 2011
- DOI:
- 10.1117/12.886690
- Bibcode:
- 2011SPIE.8073E..0LO