Fourier analysis of energy transfer data obtained by simulating a 14-MeV α-particle in water
Abstract
Data from Monte Carlo transport codes are used to model radiobiological effects. We previously reported the Fourier analysis of ionization data generated by simulating a 500-keV proton traversing water. Here, we extend Fourier analysis to energy transfer data of another radiation type, a 14-MeV α-particle. A radiobiological model based on this frequency-domain analysis views cell as an information processing system [8]. It lends itself naturally to traditional engineering analyses. One engineering principle—the output response of a linear system to random signal—is applied here to explain the fact that there is measurable difference in the magnitude of the biological effectiveness when a given biological system is irradiated with two different radiation types of the same Linear Energy Transfer (LET).
- Publication:
-
Nuclear Instruments and Methods in Physics Research B
- Pub Date:
- January 2010
- DOI:
- 10.1016/j.nimb.2009.10.170
- Bibcode:
- 2010NIMPB.268..219L