Contrast Agent Ultrasonography before and after HIFU Treatment of Parathyroid Glands
Abstract
OBJECTIVES: To observe changes in the parathyroid tissue treated by extracorporeal HIFU. MATERIAL AND METHODS: 5 patients were treated for primary hyperparathyroidism by thermally ablating enlarged parathyroid glands using an external HIFU applicator. The treated glands were visualized with B-Mode and contrast enhanced ultrasonography (CEUS) before, 1 week and 4 weeks post HIFU. Serum iPTH, calcium, and phosphorus levels were monitored before and after the treatment. RESULTS: The initial results showed a correlation between contrast agent uptake of treated parathyroid tissue, the reduction of volume of the gland and the decrease of iPTH levels. CONCLUSIONS These results show it is possible to use CEUS to monitor the thermal ablation of parathyroid glands.
- Publication:
-
9th International Symposium on Therapeutic Ultrasound: ISTU - 2009
- Pub Date:
- March 2010
- DOI:
- 10.1063/1.3367133
- Bibcode:
- 2010AIPC.1215..168K
- Keywords:
-
- ultrasonography;
- proteins;
- neuromuscular stimulation;
- 87.63.D-;
- 87.14.Lk;
- 87.17.Ee;
- Ultrasonography;
- Hormones;
- Growth and division