Neurodegeneration: A question of balance
Abstract
When a disease-associated gene is mutated, is the cellular activity of its protein product enhanced or reduced? For at least one neurodegenerative disease, spinocerebellar ataxia 1, the answer seems to be both.
- Publication:
-
Nature
- Pub Date:
- April 2008
- DOI:
- 10.1038/452707a
- Bibcode:
- 2008Natur.452..707T