BEAMS Lab: Novel approaches to finding a balance between throughput and sensitivity
Abstract
Development of 14C AMS has long pursued the twin goals of maximizing both sensitivity and precision in the interest, among others, of optimizing radiocarbon dating. Application of AMS to biomedical research is less constrained with respect to sensitivity requirements, but more demanding of high throughput. This work presents some technical and conceptual developments in sample processing and analytical instrumentation designed to streamline the process of extracting quantitative data from the various types of samples encountered in analytical biochemistry.
- Publication:
-
Nuclear Instruments and Methods in Physics Research B
- Pub Date:
- June 2007
- DOI:
- 10.1016/j.nimb.2007.02.002
- Bibcode:
- 2007NIMPB.259..773L
- Keywords:
-
- Biomedical AMS;
- High throughput;
- <SUP>14</SUP>C labeled compounds;
- Drug pharmacokinetics;
- Metabolite profiling;
- 7.75.+h;
- 82.80.Ms;
- 87.64.-t;
- Mass spectrometry;
- Spectroscopic and microscopic techniques in biophysics and medical physics
