Effect of DNA charge helicity on B-Z DNA transition
Abstract
We construct a linear Poisson-Boltzmann model for a description of the electrostatics of the B-Z DNA conformational transition. The model takes into account the helicity and double strandedness of DNA charge distribution and provides a good agreement with experimental data on the stabilization of Z-DNA at high concentrations of simple salt. The results of other models are discussed.
- Publication:
-
Journal of Chemical Physics
- Pub Date:
- September 2005
- DOI:
- 10.1063/1.2036990
- Bibcode:
- 2005JChPh.123k6101C
- Keywords:
-
- 87.14.Gg;
- 87.15.He;
- 87.10.+e;
- DNA RNA;
- Dynamics and conformational changes;
- General theory and mathematical aspects