Phospholipid Langmuir layers mixed with novel lipophilic-fullerene-derivative molecules
Abstract
A lipophilic C_60 derivative, having three lipid-like tails chemically bonded on one olefinic moiety of the C_60 cage has been synthesized, largely motivated by its potential in the biological application. With its lipid-like tails simulating largely the molecular structure of a phospholipid (DPPC), the lipophilic-C_60 molecule is expected to self-incorporate into the phospholipid membranes. Previous X-ray scattering studies showed that the lipophilic-C_60 molecule molecules could intercalate into the DPPC monolayers and modified bending and compression modulus of the host DPPC membranes significantly. In order to reveal the detailed information of their monolayer structures, combined in-situ studies of neutron reflectivity and Brewster angle microscopy have been performed at the air/water interface. The results established that the phase and ordering properties of the mixed monolayer are strongly influenced by an addition of the fullerene bearing lipid molecules. Detailed domain structures and temperature effect will be discussed.
- Publication:
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APS March Meeting Abstracts
- Pub Date:
- March 2003
- Bibcode:
- 2003APS..MAR.C1100K