Biomedical studies by PIXE
Abstract
In the present biomedical research, PIXE a powerful technique for elemental analysis was employed to illustrate the importance of multi-elemental determination of serum trace elements in two cases of great medical interest. Those are evaluation of the desferroxamine drug (DPO), a widely used therapy for patient with β-thalassemia-Major (β-thal-M), and investigation of elemental variations in blood-serum in hyperbilirubinamia new-borns before and after blood transfusion (BT). The purpose of the work is to demonstrate the various aspects of PIXE analysis by some practical examples as well as to draw some general conclusions regarding the cure of those patients with the above mentioned disorders or diseases. To present in details each case, we divide the paper in two parts: part 1 and part 2 to consider the experimental procedure as well as the results individually.
- Publication:
-
Nuclear Instruments and Methods in Physics Research B
- Pub Date:
- April 1996
- DOI:
- 10.1016/0168-583X(95)00921-3
- Bibcode:
- 1996NIMPB.109..270A