The concept of regulation for human body temperature
Abstract
1. 1.The regulated variable of human temperature regulation is certainly not a locally defined single temperature, it is probably not heat flow and not mean body temperature, but it seems to be a flexible and adaptable integrative temperature signal according to a distributed parameter control strategy. 2. 2.The regulator does not need any explicit reference, neither in the form of a neuronal signal nor in the form of the indifferent zone. 3. 3.Negative feedback is simply achieved by an odd number of negative input/output relations of the subsystems in the closed loop.
- Publication:
-
Journal of Thermal Biology
- Pub Date:
- January 1980
- DOI:
- 10.1016/0306-4565(80)90003-0
- Bibcode:
- 1980JTBio...5...75W
- Keywords:
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- Temperature regulation;
- control concept;
- distributed parameter control;
- set point;
- reference;
- fever