β-Cyclodextrin-Immobilized Ni/Graphene Electrode for Electrochemical Enantiorecognition of Phenylalanine
Abstract
In this work, a Ni/graphene (Ni/G) electrode was designed and fabricated by plasma-enhanced chemical vapor deposition (PECVD) for the ultrasensitive recognition of D- and L-phenylalanine. Through a single-step PECVD process, the Ni/G electrode can achieve better hydrophilicity and larger catalytic surface area, which is beneficial for the electrochemical recognition of bio-objects. After surface modification with β-cyclodextrin, the Ni/G electrode can distinguish D-phenylalanine from L-phenylalanine according to a 0.09 V peak shift in differential pulse voltammetry tests. Moreover, this Ni/G electrode achieved a detection limit as low as 1 nM and a wide linear range from 1 nM to 10 mM toward L-phenylalanine, with great storage stability and working stability.
- Publication:
-
Materials
- Pub Date:
- February 2020
- DOI:
- 10.3390/ma13030777
- Bibcode:
- 2020Mate...13..777C
- Keywords:
-
- graphene;
- plasma-enhanced chemical vapor deposition;
- β-cyclodextrin;
- enantiorecognition;
- phenylalanine