Non-antibacterial biogenic gold nanoparticles an ulterior drug carrier
Abstract
Gold nanoparticles have been synthesized by use of different volumes of aqueous extract which has been prepared from woman's tongue tree white flower. The gold nanoparticles and extract were tested for bactericidal qualities on B. subtilis, S. aureus, (Gram positive) and P. aeruginosa, E. coli, (Gram negative) in the concentration range of 0.5 mg ml-1 to 2.0 mg ml-1 using well diffusion. Antibacterial activity shown by all the gold nanoparticles against any of the four organisms was negligible, in spite of the fact that gold nanoparticles are conventionally known to show antibacterial properties. Lack of anti-bacterial properties of gold nanoparticles reported in this paper highlights its inert nature making it a promising alternative for its use in biomedical applications. Given that gold nanoparticles are most suited due to its targeted specificity as well as biocompatibility; these stable gold nanoparticles would be best suited as carriers for drug delivery applications.
- Publication:
-
Materials Research Express
- Pub Date:
- October 2019
- DOI:
- 10.1088/2053-1591/ab429f
- Bibcode:
- 2019MRE.....6j50c7A
- Keywords:
-
- non-antibacterial;
- biogenic;
- gold nanoparticles;
- gram positive;
- gram negative bacteria;
- drug carrier