Nowadays, the water contamination which is due to pharmaceuticals is increasing and alarming. The pharmaceuticals in water are very hazardous and toxic not only for the human life but also for environment. One of the promising methods of removing pharmaceuticals from the contaminated water is adsorption. Agricultural and industrial wastes or by-products can be used as low-cost adsorbents for pharmaceuticals removal. Low-cost adsorbents provide particular economic and environmental advantages. This paper presents an overview of utilizing of the waste-based adsorbents (mainly spent coffee grounds) for the removal of pharmaceuticals from water.