The Advanced LIGO and Advanced Virgo gravitational wave detectors have detected a population of binary black hole mergers in their first two observing runs. For each of these events, we have been able to associate a potential sky location region represented as a probability distribution on the sky. Thus, at this point we may begin to ask the question of whether this distribution agrees with the isotropic model of the Universe, or if there is any evidence of anisotropy. We perform Bayesian model selection between an isotropic and a simple anisotropic model, taking into account the anisotropic selection function caused by the underlying antenna patterns and sensitivity of the interferometers over the sidereal day. We find an inconclusive Bayes factor of 1.3: 1, suggesting that the data from the first two observing runs are insufficient to pick a preferred model. However, the first detections were mostly poorly localized in the sky (before the Advanced Virgo joined the network), spanning large portions of the sky and hampering detection of potential anisotropy. It will be appropriate to repeat this analysis with events from the recent third LIGO observational run and a more sophisticated cosmological model.