This study focuses on the reaction of the membranes of erythrocytes based on the principles that use direct effects of infrasound. The effect on biological features was investigated through the experiments on the rats. The work determined the level of electrical conductivity of blood in rats during direct, indirect and combined effects of infrasound in vivo. There was found that infrasound stimulate the immune system and therefore the results recommend that caution is take place for people who are dealing with these low frequencies. There was used many different technologies and methods, including total differential count in order to consider all of the nuances of the observed object and the main goal. The exposure to infrasound caused increase in the electric conductivity of whole blood than the control in both types of exposure which indicates a large increase of the surface charge density of erythrocyte resulted from the formation of highly reactive species such as superoxide radicals. There were found some undesired biological effects, however further work could have decreased them to a lesser extent.