Tetrazoles for biomedicine
Abstract
The tetrazole ring is an important pharmacophore. It is a structural component in many drugs, drug candidates (or lead compounds) and various biochemical reagents. This review summarizes data on the use of tetrazoles in biomedicine published in the last 10 - 15 years and also views on the nature of their biological effects. The prospects for the development of new biologically active substances containing a tetrazolyl pharmacophore are analyzed.
- Publication:
-
Russian Chemical Reviews
- Pub Date:
- June 2019
- DOI:
- 10.1070/RCR4864
- Bibcode:
- 2019RuCRv..88..644P