Computational time-of-flight diffuse optical tomography
Abstract
Imaging through a strongly diffusive medium remains an outstanding challenge, in particular in applications in biological and medical imaging. Here, we propose a method based on a single-photon time-of-flight camera that allows, in combination with computational processing of the spatial and full temporal photon distribution data, imaging of an object embedded inside a strongly diffusive medium over more than 80 transport mean free paths. The technique is contactless and requires 1 s acquisition times, thus allowing Hz frame rate imaging. The imaging depth corresponds to several centimetres of human tissue and allows us to perform deep-body imaging as a proof of principle.
- Publication:
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Nature Photonics
- Pub Date:
- May 2019
- DOI:
- 10.1038/s41566-019-0439-x
- arXiv:
- arXiv:1808.01135
- Bibcode:
- 2019NaPho..13..575L
- Keywords:
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- Physics - Optics;
- Physics - Biological Physics
- E-Print:
- 8 pages