Application of THz Fast Frequency Sweep Spectrometer for Investigation of Chemical Composition of Blood
Abstract
One of the approaches with a basically new potential for the diagnostics and treatment of socially significant diseases, such as diabetes and oncologic diseases, is based on detecting the metabolites which are indicators of diseases, including the early stage. The results of analyzing the composition of biological liquid vapor (such as blood) samples by the method of high-resolution terahertz spectroscopy based on the fast frequency sweep approach are presented. The fast frequency sweep spectrometer of the 118 ÷ 178 GHz frequency range was elaborated. A multicomponent gas mixture of products of blood evaporation and thermal decomposition at heating up to 240 °C was analyzed. A number of substances that are products of evaporation and thermal decomposition of blood components were detected. Some processes of the appearance of specific substances were discussed. The proposed approach is promising for developing a method of noninvasive medical diagnostics of pathologies and diseases, including socially significant ones.
- Publication:
-
Journal of Infrared, Millimeter, and Terahertz Waves
- Pub Date:
- 2020
- DOI:
- 10.1007/s10762-019-00656-3
- Bibcode:
- 2020JIMTW..41.1114V
- Keywords:
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- Fast frequency sweep spectrometer;
- Terahertz frequency range;
- Thermal decomposition;
- Metabolite;
- Blood vapor