We provide a novel -- and to the best of our knowledge, the first -- algorithm for high dimensional sparse regression with constant fraction of corruptions in explanatory and/or response variables. Our algorithm recovers the true sparse parameters with sub-linear sample complexity, in the presence of a constant fraction of arbitrary corruptions. Our main contribution is a robust variant of Iterative Hard Thresholding. Using this, we provide accurate estimators: when the covariance matrix in sparse regression is identity, our error guarantee is near information-theoretically optimal. We then deal with robust sparse regression with unknown structured covariance matrix. We propose a filtering algorithm which consists of a novel randomized outlier removal technique for robust sparse mean estimation that may be of interest in its own right: the filtering algorithm is flexible enough to deal with unknown covariance. Also, it is orderwise more efficient computationally than the ellipsoid algorithm. Using sub-linear sample complexity, our algorithm achieves the best known (and first) error guarantee. We demonstrate the effectiveness on large-scale sparse regression problems with arbitrary corruptions.