Beliaev damping provides a fundamental mechanism for dissipation of quasiparticles. Previous research has shown that the two-component internal degrees of freedom has no nontrivial effect on Beliaev damping. Here we provide the first example where the spinor nature of Bose gases can manifest itself in the Beliaev damping by way of spin-obit coupling. We identify novel features of the Beliaev decay rate due to spin-orbit coupling; in particular, it shows an explicit dependence on the spin-density interaction and diverges at the interaction-modified phase boundary between the zero-momentum and plane wave phases. This represents a manifestation of the effect of spin-orbit coupling in the beyond-mean-field regime, which by breaking Galilean invariance couples excitations in the density and spin channels. We further show that the measurement of the Beliaev damping rate is experimentally feasible through the measurement of spin polarizability susceptibility, which has been already achieved in spin-orbit-coupled Bose gases.