Trace elemental analysis of human breast cancerous blood by advanced PC-WDXRF technique
Abstract
The objective of this work is to quantify the trace elements of healthy and non-healthy blood samples by using advanced polychromatic source based wavelength dispersive X-ray fluorescence (PC-WDXRF) technique. The imbalances in trace elements present in the human blood directly or indirectly lead to the carcinogenic process. The trace elements 11Na, 12Mg, 15P, 16S, 17Cl, 19K, 20Ca, 26Fe, 29Cu and 30Zn are identified and their concentrations are estimated. The experimental results clearly discuss the variation and role of various trace elements present in the non-healthy blood samples relative to the healthy blood samples. These results establish future guidelines to probe the possible roles of essential trace elements in the breast carcinogenic processes. The instrumental sensitivity and detection limits for measuring the elements in the atomic range 11 ≤ Z ≤ 30 have also been discussed in the present work.
- Publication:
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Nuclear Instruments and Methods in Physics Research B
- Pub Date:
- March 2018
- DOI:
- 10.1016/j.nimb.2018.01.029
- Bibcode:
- 2018NIMPB.419...44S
- Keywords:
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- PC-WDXRF;
- Healthy and Breast cancer blood;
- Trace elements