The Mid-infrared Interferometric instrument (MIDI) at the Very Large Telescope Interferometer (VLTI) has been used to spatially resolve the dust-forming region of 14 asymptotic giant branch (AGB) stars with different chemistry (O-rich and C-rich) and variability types (Miras, semi-regular, and irregular variables). The main goal of the programme was to detect deviations from spherical symmetry in the dust-forming region of these stars. All the stars of the sample are well resolved with the VLTI, and five are asymmetric and O-rich. This finding contrasts with observations in the near-infrared, where the C-rich objects are found to be more asymmetric than the O-rich ones. The nature of the asymmetric structures so far detected (dusty discs versus blobs)remains uncertain and will require imaging on milli-arcsecond scales.