Strategies for carbohydrate model building, refinement and validation
Abstract
This article addresses many of the typical difficulties that a structural biologist may face when dealing with carbohydrates, with an emphasis on problem solving in the resolution range where X-ray crystallography and cryo-electron microscopy are expected to overlap in the next decade.
- Publication:
-
Acta Crystallographica Section D
- Pub Date:
- February 2017
- DOI:
- 10.1107/S2059798316016910
- Bibcode:
- 2017AcCrD..73..171A
- Keywords:
-
- carbohydrates;
- glycosylation;
- conformation;
- restraints;
- validation