A precise measurement of the Higgs boson couplings to bottom and top quarks is of paramount importance during the upcoming LHC runs. We present a comprehensive analysis for the Higgs production process in association with a semileptonically decaying top-quark pair and subsequent Higgs boson decay into bottom quarks. Due to the highly complex final state and large Standard Model backgrounds, measuring the signal strength in this process is known to be challenging. To maximize the sensitivity, we analyze different, statistically independent, phase space regions, where one or more of the heavy resonances are boosted. This allows us to employ jet substructure techniques, which help to reduce large t t ̄+X backgrounds. We find that combining several t t ̄H (b b ̄) phase space regions will allow one to measure deviations of the Standard Model signal strength of order 20% with 3 ab-1 .