Positive Selection or Free to Vary? Assessing the Functional Significance of Sequence Change Using Molecular Dynamics Allison, Jane R. ; Lechner, Marcus ; Hoeppner, Marc P. ; Poole, Anthony M. Abstract Publication: PLoS ONE Pub Date: February 2016 DOI: 10.1371/journal.pone.0147619 Bibcode: 2016PLoSO..1147619A