Simply and reliably detecting and quantifying entanglement outside laboratory conditions will be essential for future quantum information technologies. Here we address this issue by proposing a method for generating expressions which can perform this task between two parties who do not share a common reference frame. These reference-frame-independent expressions require only simple local measurements, which allows us to experimentally test them using an off-the-shelf entangled photon source. We show that the values of these expressions provide bounds on the concurrence of the state and demonstrate experimentally that these bounds are more reliable than values obtained from state tomography since characterizing experimental errors is easier in our setting. Furthermore, we apply this idea to other quantities, such as the Renyi and von Neumann entropies, which are also more reliably calculated directly from the raw data than from a tomographically reconstructed state. This highlights the relevance of our approach for practical quantum information applications that require entanglement.