Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing
Abstract
This work characterizes variation in recombination across the genome of a flowering plant in detail using unique population genomic and computational approaches. The resulting recombination map approaches nucleotide-level resolution and advances our understanding of basic properties of recombination, notably the findings of enhanced recombination near starts of genes, varying degrees of intensities of "hotspots," higher activity in exons than introns, and that a large fraction of the genome appears devoid of any recombination activity.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- November 2013
- DOI:
- 10.1073/pnas.1319032110
- Bibcode:
- 2013PNAS..11019478H