Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation
Abstract
In this study, we have identified a type of protein that participates in the formation of the tubular endoplasmic reticulum. This protein, protrudin, harbors hydrophobic hairpins that generate high curvature in endoplasmic reticulum tubules, as well as several domains that may link the tubular endoplasmic reticulum to the plasma membrane or other organelles.
- Publication:
-
Proceedings of the National Academy of Science
- Pub Date:
- September 2013
- DOI:
- 10.1073/pnas.1307391110
- Bibcode:
- 2013PNAS..11014954C