`Marker-of-self' functionalization of nanoscale particles through a top-down cellular membrane coating approach
Abstract
We investigate the `marker-of-self' functionalization of nanoparticles through coating of natural RBC membranes. The membrane translocation approach is shown to be highly efficient and bestows nanoparticles with correctly oriented and functional immunomodulatory proteins such as CD47 at equivalent density to natural RBCs.We investigate the `marker-of-self' functionalization of nanoparticles through coating of natural RBC membranes. The membrane translocation approach is shown to be highly efficient and bestows nanoparticles with correctly oriented and functional immunomodulatory proteins such as CD47 at equivalent density to natural RBCs.
Electronic supplementary information (ESI) available: Experimental section, theoretical calculations, and supporting figures. See DOI: 10.1039/c3nr00015j- Publication:
-
Nanoscale
- Pub Date:
- March 2013
- DOI:
- 10.1039/c3nr00015j
- Bibcode:
- 2013Nanos...5.2664H