Technological and Scientific Advances from Uhuru to Chandra

The technological and scientific advances from Uhuru to Chandra have been revolutionary. While Uhuru observations provided major discoveries ranging from accreting neutron stars in binary systems to the detection of quasars and the hot intracluster medium in clusters of galaxies, Chandra's high angular resolution has led to advances in all areas of astrophysics, from solar system objects to high redshift quasars. This contribution will highlight our advances in the study of galaxies and clusters, particularly the study of AGN feedback and major cluster mergers.