Determining Biomembrane Bending Rigidities from Simulations of Modest Size
Abstract
Thermal fluctuations of lipid orientation are analyzed to infer the bending rigidity of lipid bilayers directly from molecular simulations. Compared to the traditional analysis of thermal membrane undulations, the proposed method is reliable down to shorter wavelengths and allows for determination of the bending rigidity using smaller simulation boxes. The requisite theoretical arguments behind this analysis are presented and verified by simulations spanning a diverse range of lipid models from the literature.
- Publication:
-
Physical Review Letters
- Pub Date:
- July 2012
- DOI:
- 10.1103/PhysRevLett.109.028102
- Bibcode:
- 2012PhRvL.109b8102W
- Keywords:
-
- 87.16.dj;
- 46.70.Hg;
- 87.14.Cc;
- 87.16.dm;
- Dynamics and fluctuations;
- Membranes rods and strings;
- Lipids;
- Mechanical properties and rheology