High heat flow, high surface topography, and widespread volcanism indicate that the lithospheric mantle of typical cratonic character of the North China Craton has been seriously destroyed in its eastern half. However, the mechanism of this process remains open to intense debate. Here lithosphere folding-induced lithospheric mantle removal is proposed as a new mechanism for the destruction of the craton. Four main NNE-SSW-striking lithospheric-scale anticlines and synclines are recognized within North China east of the Helan fold-and-thrust belt. The lithosphere folding occurred possibly during the Late Triassic through Jurassic when the Yangzi Craton collided with the North China Craton. It was accompanied or followed by lithospheric dripping, and could have possibly induced the lithosphere foundering of the North China Craton. The lithosphere folding would have modified the lithosphere morphology, creating significant undulation in the lithospheric base and thus causing variations of the patterns of the small-scale convection. It also could have provoked the formation of new shear zones liable to impregnation of magma, producing linear incisions at the cratonic base and resulting in foundering of lithospheric mantle blocks. Furthermore, it generated thickening of the lithosphere or the lower crust and initiated the destabilization and subsequent removal of the lithospheric mantle.