The cataclysmic variable SDSS 154453 + 2553 was recently identified in the Sloan Digital Sky Survey. We obtained spectra and photometry at the MDM Observatory, which revealed an eclipse with a 6.03 hr period. The Hα emission line exhibits a strong rotational disturbance during eclipse, indicating that it arises in an accretion disk. A contribution from an M-type companion is also observed. Time-series photometry during eclipse gives an ephemeris of 2454878.0062(15) + 0.251282(2)E. We present spectroscopy through the orbit and eclipse photometry. Our analysis of the secondary star indicates a distance of 800 ± 180 pc.