Cancer: When catastrophe strikes a cell
Abstract
In 2-3% of cancers, a single genetic event may have led to hundreds of genomic rearrangements confined to just one or a few chromosomes. This finding challenges the conventional view of how mutations accumulate in oncogenesis.
- Publication:
-
Nature
- Pub Date:
- February 2011
- DOI:
- 10.1038/470476a
- Bibcode:
- 2011Natur.470..476T