As an application of our recent observational error model, we present the astrometric masses of 26 main-belt asteroids. We also present an integrated ephemeris of 300 large asteroids, which was used in the mass determination algorithm to model significant perturbations from the rest of the main belt. After combining our mass estimates with those of other authors, we study the bulk porosities of over 50 main-belt asteroids and observe that asteroids as large as 300 km in diameter may be loose aggregates. This finding may place specific constraints on models of main-belt collisional evolution. Additionally, we observe that C-group asteroids tend to have significantly higher macroporosity than S-group asteroids.