Perspectives on Porous Media MR in Clinical MRI
Abstract
Many goals and challenges of research in natural or synthetic porous media are mirrored in quantitative medical MRI. This review will describe examples where MR techniques used in porous media (particularly diffusion-weighted imaging (DWI)) are applied to physiological pathologies. Tissue microstructure is one area with great overlap with porous media science. Diffusion-weighting (esp. in neurological tissue) has motivated models with explicit physical dimensions, statistical parameters, empirical descriptors, or hybrids thereof. Another clinically relevant microscopic process is active flow. Renal (kidney) tissue possesses significant active vascular / tubular transport that manifests as "pseudodiffusion." Cancerous lesions involve anomalies in both structure and flow. The tools of magnetic resonance and their interpretation in porous media has had great impact on clinical MRI, and continued cross-fertilization of ideas can only enhance the progress of both fields.
- Publication:
-
Magnetic Resonance in Porous Media
- Pub Date:
- March 2011
- DOI:
- 10.1063/1.3562222
- Bibcode:
- 2011AIPC.1330...13S
- Keywords:
-
- porous materials;
- crystal microstructure;
- diffusion;
- pseudopotential methods;
- 82.33.Ln;
- 81.30.Bx;
- 82.40.Ck;
- 71.15.Dx;
- Reactions in sol gels aerogels porous media;
- Phase diagrams of metals and alloys;
- Pattern formation in reactions with diffusion flow and heat transfer;
- Computational methodology