In this paper, we propose a new approach for keypoint-based object detection. Traditional keypoint-based methods consist in classifying individual points and using pose estimation to discard misclassifications. Since a single point carries no relational features, such methods inherently restrict the usage of structural information to the pose estimation phase. Therefore, the classifier considers purely appearance-based feature vectors, thus requiring computationally expensive feature extraction or complex probabilistic modelling to achieve satisfactory robustness. In contrast, our approach consists in classifying graphs of keypoints, which incorporates structural information during the classification phase and allows the extraction of simpler feature vectors that are naturally robust. In the present work, 3-vertices graphs have been considered, though the methodology is general and larger order graphs may be adopted. Successful experimental results obtained for real-time object detection in video sequences are reported.