Cu-catalyzed cross-dehydrogenative coupling: A versatile strategy for C-C bond formations via the oxidative activation of sp3 C-H bonds
Abstract
Cu-catalyzed cross-dehydrogenative coupling (CDC) methodologies were developed based on the oxidative activation of sp3 C-H bonds adjacent to a nitrogen atom. Various sp, sp2, and sp3 C-H bonds of pronucleophiles were used in the Cu-catalyzed CDC reactions. Based on these results, the mechanisms of the CDC reactions also are discussed.
- Publication:
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Proceedings of the National Academy of Science
- Pub Date:
- June 2006
- DOI:
- 10.1073/pnas.0601687103
- Bibcode:
- 2006PNAS..103.8928L
- Keywords:
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- PHYSICAL SCIENCES / CHEMISTRY