Cell biology Sterol sensor comes up for air
Abstract
In one example of a feedback mechanism in mammals, cells switch cholesterol synthesis on or off depending on the availability of sterol. A rewired version of this pathway in yeast acts instead as an oxygen sensor.
- Publication:
-
Nature
- Pub Date:
- May 2005
- DOI:
- 10.1038/435037a
- Bibcode:
- 2005Natur.435...37G